TD-0212
Modify Date: 2025-08-27 10:03:40
TD-0212 structure
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Common Name | TD-0212 | ||
|---|---|---|---|---|
| CAS Number | 1073549-10-6 | Molecular Weight | 527.65 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H34FN3O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TD-0212TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP[1]. |
| Name | TD-0212 |
|---|
| Description | TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP[1]. |
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| Related Catalog | |
| Target |
pKi: 8.9 (AT1) pIC50: 9.2 (NEP)[1]. |
| References |
| Molecular Formula | C28H34FN3O4S |
|---|---|
| Molecular Weight | 527.65 |
| InChIKey | BSJZYWSFNCKCDR-VWLOTQADSA-N |
| SMILES | CCOc1nc(CC)c(CNC(=O)C(S)CC(C)C)n1Cc1ccc(-c2ccccc2C(=O)O)cc1F |