TD-0212

Modify Date: 2024-01-11 18:36:46

TD-0212 structure	Common Name	TD-0212
	CAS Number	1073549-10-6	Molecular Weight	527.65
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₄FN₃O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TD-0212

TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP[1].

Name	TD-0212

Description	TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor Signaling Pathways >> Metabolic Enzyme/Protease >> Neprilysin
Target	pKi: 8.9 (AT1) pIC50: 9.2 (NEP)[1].
References	[1]. McKinnell RM, et al. Discovery of TD-0212, an Orally Active Dual Pharmacology AT1 Antagonist and Neprilysin Inhibitor (ARNI). ACS Med Chem Lett. 2018 Dec 3;10(1):86-91.

Molecular Formula	C₂₈H₃₄FN₃O₄S
Molecular Weight	527.65

DC Chemicals Limited
China
Product Name: TD-0212
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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