1621694-21-0
1621694-21-0 structure
- Name: TD-1
- Chemical Name: TD-1
- CAS Number: 1621694-21-0
- Molecular Formula: C20H16N6O4S2
- Molecular Weight: 468.506
- Create Date: 2020-01-12 17:20:22
- Modify Date: 2025-08-21 15:09:36
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Hemoglobin modulator TD-1 (TD-1) is a novel allosteric effector of hemoglobin that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling; increases the oxygen affinity of sickle hemoglobin and inhibits in vitro hypoxia-induced sickling of red blood cells in patients with sickle cell disease without causing hemolysis; a novel lead molecule for the treatment of patients with sickle cell disease.
| Name | TD-1 |
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| Description | Hemoglobin modulator TD-1 (TD-1) is a novel allosteric effector of hemoglobin that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling; increases the oxygen affinity of sickle hemoglobin and inhibits in vitro hypoxia-induced sickling of red blood cells in patients with sickle cell disease without causing hemolysis; a novel lead molecule for the treatment of patients with sickle cell disease. |
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| References | References 1. Nakagawa A, et al. ACS Chem Biol. 2014 Oct 17;9(10):2318-25. View Related Products by Target Other Targets |
| Molecular Formula | C20H16N6O4S2 |
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| Molecular Weight | 468.506 |