TD-1

Modify Date: 2024-01-03 07:25:55

TD-1 Structure
TD-1 structure
Common Name TD-1
CAS Number 1621694-21-0 Molecular Weight 468.506
Density N/A Boiling Point N/A
Molecular Formula C20H16N6O4S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TD-1


Hemoglobin modulator TD-1 (TD-1) is a novel allosteric effector of hemoglobin that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling; increases the oxygen affinity of sickle hemoglobin and inhibits in vitro hypoxia-induced sickling of red blood cells in patients with sickle cell disease without causing hemolysis; a novel lead molecule for the treatment of patients with sickle cell disease.

 Names

Name TD-1

 TD-1 Biological Activity

Description Hemoglobin modulator TD-1 (TD-1) is a novel allosteric effector of hemoglobin that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling; increases the oxygen affinity of sickle hemoglobin and inhibits in vitro hypoxia-induced sickling of red blood cells in patients with sickle cell disease without causing hemolysis; a novel lead molecule for the treatment of patients with sickle cell disease.
References References 1. Nakagawa A, et al. ACS Chem Biol. 2014 Oct 17;9(10):2318-25. View Related Products by Target Other Targets

 Chemical & Physical Properties

Molecular Formula C20H16N6O4S2
Molecular Weight 468.506