rac trans-2-Phenylcyclopropylamine-d5 Hydrochloride

Modify Date: 2024-04-02 17:30:00

rac trans-2-Phenylcyclopropylamine-d5 Hydrochloride Structure
rac trans-2-Phenylcyclopropylamine-d5 Hydrochloride structure
Common Name rac trans-2-Phenylcyclopropylamine-d5 Hydrochloride
CAS Number 107077-98-5 Molecular Weight 174.68200
Density N/A Boiling Point N/A
Molecular Formula C9H7D5ClN Melting Point 162-169ºC
MSDS N/A Flash Point N/A

 Use of rac trans-2-Phenylcyclopropylamine-d5 Hydrochloride


(rel)-Tranylcypromine D5 hydrochloride (2-Phenylcyclopropylamine D5 hydrochloride) is a deuterium labeled (rel)-Tranylcypromine hydrochloride. (rel)-Tranylcypromine hydrochloride is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. (rel)-Tranylcypromine hydrochloride is also a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis[1][2].

 Names

Name rac trans-2-Phenylcyclopropylamine-d5 Hydrochloride
Synonym More Synonyms

  Biological Activity

Description (rel)-Tranylcypromine D5 hydrochloride (2-Phenylcyclopropylamine D5 hydrochloride) is a deuterium labeled (rel)-Tranylcypromine hydrochloride. (rel)-Tranylcypromine hydrochloride is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. (rel)-Tranylcypromine hydrochloride is also a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis[1][2].
Related Catalog
Target

Monoamine oxidase (MAO)[1] Lysine-specific demethylase 1 (LSD1)[2]

References

[1]. Caraci F, et al. Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity. Eur J Pharmacol. 2015 Oct 5;764:256-263.

[2]. Sun Q, et al. Tranylcypromine, a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis. Reprod Biol Endocrinol. 2016 Apr 9;14:17.

 Chemical & Physical Properties

Melting Point 162-169ºC
Molecular Formula C9H7D5ClN
Molecular Weight 174.68200
Exact Mass 174.09700
PSA 26.02000
LogP 3.00350

 Safety Information

Hazard Codes Xi

 Synonyms

(1R,2S)-2-(2,3,4,5,6-pentadeuteriophenyl)cyclopropan-1-amine,hydrochloride
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