107077-98-5

107077-98-5 structure

Name: rac trans-2-Phenylcyclopropylamine-d5 Hydrochloride
Chemical Name: rac trans-2-Phenylcyclopropylamine-d5 Hydrochloride
CAS Number: 107077-98-5
Molecular Formula: C₉H₇D₅ClN
Molecular Weight: 174.68200
Catalog: Signaling Pathways Epigenetics Histone Demethylase
Create Date: 2018-12-12 14:21:24
Modify Date: 2024-04-02 17:30:00
(rel)-Tranylcypromine D5 hydrochloride (2-Phenylcyclopropylamine D5 hydrochloride) is a deuterium labeled (rel)-Tranylcypromine hydrochloride. (rel)-Tranylcypromine hydrochloride is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. (rel)-Tranylcypromine hydrochloride is also a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis[1][2].

Name	rac trans-2-Phenylcyclopropylamine-d5 Hydrochloride
Synonyms	(1R,2S)-2-(2,3,4,5,6-pentadeuteriophenyl)cyclopropan-1-amine,hydrochloride

Description	(rel)-Tranylcypromine D5 hydrochloride (2-Phenylcyclopropylamine D5 hydrochloride) is a deuterium labeled (rel)-Tranylcypromine hydrochloride. (rel)-Tranylcypromine hydrochloride is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. (rel)-Tranylcypromine hydrochloride is also a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis[1][2].
Related Catalog	Signaling Pathways >> Epigenetics >> Histone Demethylase Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
Target	Monoamine oxidase (MAO)[1] Lysine-specific demethylase 1 (LSD1)[2]
References	[1]. Caraci F, et al. Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity. Eur J Pharmacol. 2015 Oct 5;764:256-263. [2]. Sun Q, et al. Tranylcypromine, a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis. Reprod Biol Endocrinol. 2016 Apr 9;14:17.

Hazard Codes	Xi