(R)-(-)-O-Desmethyl Venlafaxine D6

Modify Date: 2024-01-04 19:59:01

(R)-(-)-O-Desmethyl Venlafaxine D6 Structure
(R)-(-)-O-Desmethyl Venlafaxine D6 structure
Common Name (R)-(-)-O-Desmethyl Venlafaxine D6
CAS Number 1062609-96-4 Molecular Weight 269.412
Density 1.1±0.1 g/cm3 Boiling Point 403.8±25.0 °C at 760 mmHg
Molecular Formula C16H19D6NO2 Melting Point N/A
MSDS N/A Flash Point 193.2±21.8 °C

 Use of (R)-(-)-O-Desmethyl Venlafaxine D6


(R)-(-)-O-Desmethyl Venlafaxine D6 is the deuterium labeled (R)-(-)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].

 Names

Name 4-[(1R)-2-{Bis[(2H3)methyl]amino}-1-(1-hydroxycyclohexyl)ethyl]phenol
Synonym More Synonyms

 (R)-(-)-O-Desmethyl Venlafaxine D6 Biological Activity

Description (R)-(-)-O-Desmethyl Venlafaxine D6 is the deuterium labeled (R)-(-)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].
Related Catalog
References

[1]. Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28.

[2]. F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 403.8±25.0 °C at 760 mmHg
Molecular Formula C16H19D6NO2
Molecular Weight 269.412
Flash Point 193.2±21.8 °C
Exact Mass 269.226196
LogP 2.26
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.573

 Synonyms

4-[(1R)-2-{Bis[(2H3)methyl]amino}-1-(1-hydroxycyclohexyl)ethyl]phenol
Phenol, 4-[(1R)-2-(dimethyl-d3-amino)-1-(1-hydroxycyclohexyl)ethyl]-