142761-12-4

142761-12-4 structure

Name: (S)-(+)-O-Desmethyl Venlafaxine
Chemical Name: S-(+)-O-Desmethyl Venlafaxine
CAS Number: 142761-12-4
Molecular Formula: C₁₆H₂₅NO₂
Molecular Weight: 263.37500
Catalog: Research Areas Neurological Disease
Create Date: 2017-02-28 10:35:29
Modify Date: 2025-08-25 17:45:28
(S)-(+)-O-Desmethyl Venlafaxine is a S-enantiomer of O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].

Name	S-(+)-O-Desmethyl Venlafaxine
Synonyms	4-[(1S)-2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol

Description	(S)-(+)-O-Desmethyl Venlafaxine is a S-enantiomer of O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28. [2]. F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.

93413-46-8

~73%

142761-12-4

Literature: Solvay Pharmaceuticals, B.V. Patent: US2009/5455 A1, 2009 ; Location in patent: Page/Page column 7 ;

Precursor 1
93413-46-8
DownStream 0