RETRA hydrobromide
Modify Date: 2024-11-30 18:02:15
RETRA hydrobromide structure
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Common Name | RETRA hydrobromide | ||
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| CAS Number | 1035875-01-4 | Molecular Weight | 350.245 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C11N11NO3S2.HBr | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RETRA hydrobromideRETRA hydrobromide is a small molecule mutant p53 reactivator that activates a set of p53-regulated genes and specifically suppresses mutant p53-bearing tumor cells in vitro and in mouse xenograft; increases in the expression level of p73, releases p73 and poduces tumor-suppressor effects similar to the functional reactivation of p53; a p73 activator. |
| Name | RETRA hydrobromide |
|---|
| Description | RETRA hydrobromide is a small molecule mutant p53 reactivator that activates a set of p53-regulated genes and specifically suppresses mutant p53-bearing tumor cells in vitro and in mouse xenograft; increases in the expression level of p73, releases p73 and poduces tumor-suppressor effects similar to the functional reactivation of p53; a p73 activator. |
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| References | References 1. Kravchenko JE, et al. Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6302-7. 2. Sonnemann J, et al. Eur J Cancer. 2015 May;51(7):841-51. 3. Santag S, et al. Oncogene. 2013 Aug 8;32(32):3676-85. View Related Products by Target MDM2-p53 |
| Molecular Formula | C11N11NO3S2.HBr |
|---|---|
| Molecular Weight | 350.245 |