A1AR antagonist 4

Modify Date: 2024-04-06 20:45:59

A1AR antagonist 4 Structure
A1AR antagonist 4 structure
Common Name A1AR antagonist 4
CAS Number 1031993-35-7 Molecular Weight 375.46
Density N/A Boiling Point N/A
Molecular Formula C23H25N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of A1AR antagonist 4


A1AR antagonist 4 (compound 22) is a potent and selective A1AR (A1 adenosine receptor) antagonist, with a pIC50 of 5.51 and a pKi of 6.29[1].

 Names

Name A1AR antagonist 4

 A1AR antagonist 4 Biological Activity

Description A1AR antagonist 4 (compound 22) is a potent and selective A1AR (A1 adenosine receptor) antagonist, with a pIC50 of 5.51 and a pKi of 6.29[1].
Related Catalog
Target

hA1AR:6.29 (pKi)

hA2AAR:<4 (pKi)

References

[1]. Wei Y, et al. Identification of new potent A1 adenosine receptor antagonists using a multistage virtual screening approach. Eur J Med Chem. 2020 Feb 1;187:111936.

 Chemical & Physical Properties

Molecular Formula C23H25N3O2
Molecular Weight 375.46