2242465-58-1

2242465-58-1 structure

Name: AHR antagonist 4
Chemical Name: AHR antagonist 4
CAS Number: 2242465-58-1
Molecular Formula: C₂₀H₁₄F₆N₄O₄
Molecular Weight: 488.34
Catalog: Signaling Pathways Immunology/Inflammation Aryl Hydrocarbon Receptor
Create Date: 2020-04-05 10:07:06
Modify Date: 2025-09-16 18:45:43
AHR antagonist 4 is a 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamide compound and a potent aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 293, has an IC50 of 82.2 nM. AHR antagonist 4 has anti-cancer effects[1].

Name	AHR antagonist 4

Description	AHR antagonist 4 is a 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamide compound and a potent aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 293, has an IC50 of 82.2 nM. AHR antagonist 4 has anti-cancer effects[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> Aryl Hydrocarbon Receptor
Target	IC50: 82.2 nM (Aryl hydrocarbon receptor (AHR))[1]
References	[1]. Ilona GUTCHER, et al. 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer. WO2018146010A1.

Molecular Formula	C₂₀H₁₄F₆N₄O₄
Molecular Weight	488.34