ARN2966
Modify Date: 2024-01-03 16:16:09
ARN2966 structure
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Common Name | ARN2966 | ||
|---|---|---|---|---|
| CAS Number | 102212-26-0 | Molecular Weight | 200.23600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H12N2O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of ARN2966ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ. IC50 value: Target: AβThis potent post-transcriptional modulation of APP expression differs from other mechanisms such as inhibition of secretases. Secretase inhibitors have been pursued as disease modifying strategies by a number of pharmaceutical firms but they have encountered numerous setbacks during clinical development. ARN2966 is non toxic, orally absorbable, blood-brain-barrier penetrable, and effective in vitro and in vivo. |
| Name | N-(2-hydroxyphenyl)-N-(2-pyridylmethyl)amine |
|---|---|
| Synonym | More Synonyms |
| Description | ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ. IC50 value: Target: AβThis potent post-transcriptional modulation of APP expression differs from other mechanisms such as inhibition of secretases. Secretase inhibitors have been pursued as disease modifying strategies by a number of pharmaceutical firms but they have encountered numerous setbacks during clinical development. ARN2966 is non toxic, orally absorbable, blood-brain-barrier penetrable, and effective in vitro and in vivo. |
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| Related Catalog | |
| References |
| Molecular Formula | C12H12N2O |
|---|---|
| Molecular Weight | 200.23600 |
| Exact Mass | 200.09500 |
| PSA | 45.15000 |
| LogP | 2.47230 |
| Storage condition | 2-8℃ |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| RIDADR | NONH for all modes of transport |
| 2-[(Pyridin-2-ylmethyl)-amino]-phenol |
| 2-N-(2-pyridylmethyl)aminophenol |
| (2-Hydroxyphenyl)(2-pyridylmethyl)amin |
| 2-[(pyridine-2-ylmethyl)-amino]phenol |
| ARN2966 |
| 2-PMAP |