Ipatasertib-NH2 dihydrochloride
Modify Date: 2025-08-27 08:29:58
Ipatasertib-NH2 dihydrochloride structure
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Common Name | Ipatasertib-NH2 dihydrochloride | ||
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| CAS Number | 1001264-73-8 | Molecular Weight | 488.84 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H28Cl3N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Ipatasertib-NH2 dihydrochlorideIpatasertib-NH2 dihydrochloride is a ligand for target protein AKT for PROTAC (INY-03-041). INY-03-041 is composed of Ipatasertib-NH2, a ten-hydrocarbon linker, and a CRBN ligand Lenalidomide for E3 ubiquitin ligase[1]. |
| Name | Ipatasertib-NH2 dihydrochloride |
|---|
| Description | Ipatasertib-NH2 dihydrochloride is a ligand for target protein AKT for PROTAC (INY-03-041). INY-03-041 is composed of Ipatasertib-NH2, a ten-hydrocarbon linker, and a CRBN ligand Lenalidomide for E3 ubiquitin ligase[1]. |
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| Related Catalog | |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C21H28Cl3N5O2 |
|---|---|
| Molecular Weight | 488.84 |
| InChIKey | JUPJLFOYULADQR-AXGUDRQCSA-N |
| SMILES | CC1CC(O)c2ncnc(N3CCN(C(=O)C(CN)c4ccc(Cl)cc4)CC3)c21.Cl.Cl |
| Storage condition | 2-8°C |