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660-88-8

660-88-8 structure
660-88-8 structure
Name 5-aminopentanoic acid
Synonyms 5-amino valeric acid
δ-Aminovaleric acid
EINECS 211-544-5
5-Aminopentanoic acid
Pentanoic acid, 5-amino-
5-Aminovaleric acid
MFCD00008232
H-5-Ava-OH
Description 5-Aminovaleric acid is believed to act as a methylene homologue of gamma-aminobutyric acid (GABA) and functions as a weak GABA agonist.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro 5-Aminovaleric acid is a normal metabolite present in human saliva, with a tendency to elevated concentration in patients with chronic periodontitis[1]. 5-Aminovaleric acid is also believed to act as a methylene homologue of gamma-aminobutyric acid (GABA) and functions as a weak GABA agonist[2]. It is also known as an antifibrinolytic amino acid analog and so it functions as a weak inhibitor of the blood clotting pathway[3].
References

[1]. Syrjänen S, et al. Free amino-acid content of wax-stimulated human whole saliva as related to periodontal disease. Arch Oral Biol. 1987;32(9):607-10.

[2]. Callery PS, et al. 1-Piperideine as an in vivo precursor of the gamma-aminobutyric acid homologue 5-aminopentanoic acid. J Neurochem. 1985 Sep;45(3):946-8.

[3]. Cole KR, et al. The binding of antifibrinolytic amino acids to kringle-4-containing fragments of plasminogen. Arch Biochem Biophys. 1984 Mar;229(2):568-75.
Density 1.1±0.1 g/cm3
Boiling Point 247.5±23.0 °C at 760 mmHg
Melting Point 158-161 °C(lit.)
Molecular Formula C5H11NO2
Molecular Weight 117.146
Flash Point 103.5±22.6 °C
Exact Mass 117.078979
PSA 63.32000
LogP -0.34
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.466
Storage condition Store at 0-5°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
Risk Phrases R20/21/22
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2922499990
HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%
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title: CAS No. 660-88-8 | Chemsrc address: https://www.chemsrc.com/en/baike/704699.html

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