Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Spaglumic Acid
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

GL Biochem (Shanghai) Ltd.
China
Product Name: Ac-Asp-Glu-OH
Price: $Inquiry/1kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang
Email: ymbetter@glbiochem.com

3106-85-2

3106-85-2 structure

3106-85-2 structure

Name: Spaglumic Acid
Chemical Name: n-acetyl-asp-glu
CAS Number: 3106-85-2
Molecular Formula: C₁₁H₁₆N₂O₈
Molecular Weight: 304.253
Catalog: Biochemical Peptide
Create Date: 2018-02-14 08:00:00
Modify Date: 2025-08-27 12:20:33
Isospaglumic acid is a neuropeptide found in millimolar concentrations in brain.

Name	n-acetyl-asp-glu
Synonyms	N-Acetyl-L-aspartyl-L-glutamic acid N-acetyl-1-aspartylglutamic acid NAAGA AC-ASP-GLU SPAGLUMIC ACID N-(N-Acetyl-L-a-aspartyl)-L-glutamic Acid N-acetyl-L-aspartyl-L-glutamate N-Acetyl-L-α-aspartyl-L-glutamic acid isospaglumic acid L-Glutamic acid, N-acetyl-L-α-aspartyl- AC-ASP-GLU H2O AC-ASP-GLU-OH MFCD00076652 Tacrine hydrochloride N-acetyl-aspartatylglutamate N-(N-Acetyl-L-α-aspartyl)-L-glutamic acid glutamic acid, N-acetylaspartyl- ACETYL-D-E Naaxia NAAG N-Acetylaspartylglutamic acid NAAG Spaglumic acid

Description	Isospaglumic acid is a neuropeptide found in millimolar concentrations in brain.
Related Catalog	Natural Products >> Acids and Aldehydes Research Areas >> Neurological Disease
Target	Human Endogenous Metabolite
In Vitro	Isospaglumic acid (N-Acetylaspartylglutamate; NAAG) is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. NAAG is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes. The levels of NAAG and the activity of carboxypeptidase II are altered in a regionally specific fashion in several neuropsychiatric disorders[1].
References	[1]. Coyle JT. The nagging question of the function of N-acetylaspartylglutamate. Neurobiol Dis. 1997;4(3-4):231-8.

Density	1.5±0.1 g/cm3
Boiling Point	769.5±60.0 °C at 760 mmHg
Molecular Formula	C₁₁H₁₆N₂O₈
Molecular Weight	304.253
Flash Point	419.1±32.9 °C
Exact Mass	304.090668
PSA	170.10000
LogP	-1.96
Vapour Pressure	0.0±5.7 mmHg at 25°C
Index of Refraction	1.540
Storage condition	−20°C
Water Solubility	H2O: 50 mg/mL

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2924199090

Precursor 1
10144-33-9
DownStream 2
56-86-0 997-55-7

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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