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2002-35-9

2002-35-9 structure
2002-35-9 structure
  • Name: n6-methyl-2'-deoxy-adenosine
  • Chemical Name: (2R,3S,5R)-2-(hydroxymethyl)-5-[6-(methylamino)purin-9-yl]oxolan-3-ol
  • CAS Number: 2002-35-9
  • Molecular Formula: C11H15N5O3
  • Molecular Weight: 265.27
  • Catalog: Biochemical Nucleoside drugs Deoxynucleotides and their analogues
  • Create Date: 2018-07-03 23:13:18
  • Modify Date: 2024-01-14 22:34:26
  • N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name (2R,3S,5R)-2-(hydroxymethyl)-5-[6-(methylamino)purin-9-yl]oxolan-3-ol
Synonyms N-6-methyl-2'-deoxyribofuranosil adenine
N6-Methyl-2'-desoxy-adenosin
N6-Methyldeoxyadenosine
2'-Deoxy-N6-methylado
Adenosine,2'-deoxy-N-methyl
N6-Methyl-2'-deoxyadenosine
2'-deoxy-N6-methyladenosine
N6-methyl-2'-deoxy-adenosine
Description N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 1.72g/cm3
Boiling Point 603.6ºC at 760mmHg
Molecular Formula C11H15N5O3
Molecular Weight 265.27
Flash Point 318.8ºC
Exact Mass 265.11700
PSA 105.32000
Appearance Powder | White to Off-white
Vapour Pressure 2.03E-15mmHg at 25°C
Index of Refraction 1.78
Storage condition −20°C
Water Solubility Soluble in water
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 29349990

~78%

2002-35-9 structure

2002-35-9

Literature: Helvetica Chimica Acta, , vol. 69, p. 1034 - 1040

~31%

2002-35-9 structure

2002-35-9

Detail
Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2787 - 2792

~21%

2002-35-9 structure

2002-35-9

Detail
Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1327 - 1330

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2002-35-9 structure

2002-35-9

Literature: Collection of Czechoslovak Chemical Communications, , vol. 59, # 10 p. 2303 - 2330