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60-19-5

60-19-5 structure
60-19-5 structure
  • Name: Tyramine
  • Chemical Name: Tyramine hydrochloride
  • CAS Number: 60-19-5
  • Molecular Formula: C8H12ClNO
  • Molecular Weight: 137.179
  • Catalog: Research Areas Others
  • Create Date: 2018-10-01 18:59:19
  • Modify Date: 2025-08-23 18:11:34
  • Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods[1].
Name Tyramine hydrochloride
Synonyms p-b-Aminoethylphenol
P-hydroxy-b-phenylethylamine
Z2R DQ
MFCD00012682
4-Hydroxy phenylethylamine
EINECS 206-446-4
4-hydroxy-Benzeneethanamine
Phenol, p- (2-aminoethyl)-
4-Hydroxy-β-phenylethylamine
4- (2-aminoethyl)-Phenol
p-(2-aminoethyl)-Phenol
α-(4-Hydroxyphenyl)-β-aminoethane
β-(4-Hydroxyphenyl)ethylamine
2-p-Hydroxyphenylethylamine
a-(4-Hydroxyphenyl)-b-aminoethane
p-β-Aminoethylphenol
4-hydroxy-phenethylamine
p-Hydroxy-β-phenethylamine
4-(2-Aminoethyl)phenol
4-(2-aminoethyl)phenol,hydrochloride
b-(4-Hydroxyphenyl)ethylamine
Phenol, 4-(2-aminoethyl)-
P-hydroxy-β-phenylethylamine
Tyramine base
P-hydroxy-b-phenethylamine
Description Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods[1].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Tyramine is normally broken down in your body by an enzyme called MAO (monoamine oxidase)[1].
References

[1]. C Brown , et al. The Monoamine Oxidase Inhibitor-Tyramine Interaction. J Clin Pharmacol. 1989 Jun;29(6):529-32.
Density 1.1±0.1 g/cm3
Boiling Point 325.2±0.0 °C at 760 mmHg
Melting Point 253-255 °C(lit.)
Molecular Formula C8H12ClNO
Molecular Weight 137.179
Flash Point 119.2±20.4 °C
Exact Mass 137.084061
PSA 46.25000
LogP 0.72
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.577
Storage condition Store at RT.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SJ6050000
CHEMICAL NAME :
Phenol, p-(2-aminoethyl)-, monohydrochloride
CAS REGISTRY NUMBER :
60-19-5
LAST UPDATED :
199709
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C8-H11-N-O.Cl-H
MOLECULAR WEIGHT :
173.66
WISWESSER LINE NOTATION :
Z2R DQ &G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
710 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
208 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1044 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - mouse Lymphocyte
DOSE/DURATION :
2530 umol/L
REFERENCE :
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 3,193,1988
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S22-S24/25-S36-S26
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS NL4375000
HS Code 29222900
HS Code 2922299090
Summary 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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title: CAS No. 60-19-5 | Chemsrc address: https://www.chemsrc.com/en/baike/509756.html

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