113231-05-3

113231-05-3 structure

Name: N,N-Bis(carboxymethyl)-L-lysine
Chemical Name: (S)-N-(5-AMino-1-carboxypentyl)iMinodiacetic acid hydrate
CAS Number: 113231-05-3
Molecular Formula: C₁₀H₁₈N₂O₆
Molecular Weight: 262.26
Catalog: Biochemical Amino acids and their derivatives Lysine derivative
Create Date: 2018-12-28 19:07:41
Modify Date: 2024-01-02 18:47:01
Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC50 of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study[1][2][3].

Name	(S)-N-(5-AMino-1-carboxypentyl)iMinodiacetic acid hydrate
Synonyms	BIS-BOC-L-CYSTINE MFCD00237437 BOC-L-CYSTINE extrapure N,N-Bis(carboxymethyl)-L-lysine N N-BOC-L-CYSTEINE L-Lysine, N,N-bis(carboxymethyl)- N,N'-di-Boc-cystine N,N'-Bis-Boc-cystine BOC-L-CYSTINE N,N-di-Boc-L-cystine

Description	Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC50 of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Pydi SP, et al. Amino acid derivatives as bitter taste receptor (T2R) blockers. J Biol Chem. 2014;289(36):25054-25066. [2]. Sidhu C, et al. Regulation of Rac1 GTPase activity by quinine through G-protein and bitter taste receptor T2R4. Mol Cell Biochem. 2017;426(1-2):129-136. [3]. Masamoto M, et al. Yoshida R. Effects of bitter receptor antagonists on behavioral lick responses of mice. Neurosci Lett. 2020;730:135041.

Density	1.4±0.1 g/cm3
Boiling Point	537.8±50.0 °C at 760 mmHg
Melting Point	>208°C
Molecular Formula	C₁₀H₁₈N₂O₆
Molecular Weight	262.26
Flash Point	279.0±30.1 °C
Exact Mass	262.116486
PSA	141.16000
LogP	-1.77
Vapour Pressure	0.0±3.1 mmHg at 25°C
Index of Refraction	1.552
Storage condition	Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Stability	Moisture Sensitive

113231-04-2

~77%

113231-05-3

205379-08-4

113231-05-3

Literature: Journal of the American Chemical Society, , vol. 127, # 29 p. 10205 - 10215

1155-64-2

113231-05-3

205379-07-3

113231-05-3

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%