62717-63-9
62717-63-9 structure
- Name: SKF-75670
- Chemical Name: 3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol,hydrobromide
- CAS Number: 62717-63-9
- Molecular Formula: C17H20BrNO2
- Molecular Weight: 350.25
- Create Date: 2016-04-21 07:22:54
- Modify Date: 2024-01-02 19:47:23
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SKF-75670 hydrochloride is a Dopamine D1 receptor partial agonist. SKF-75670 hydrochloride is also a Cocaine antagonist[1][2][3].
| Name | 3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol,hydrobromide |
|---|---|
| Synonyms |
(R)-2,3,4,5-tetrahydro-7,8-dihydroxy-3-methyl-1-phenyl-1H-3-benzazepine hydrobromide
7,8-dihydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide |
| Description | SKF-75670 hydrochloride is a Dopamine D1 receptor partial agonist. SKF-75670 hydrochloride is also a Cocaine antagonist[1][2][3]. |
|---|---|
| Related Catalog | |
| Target |
D1 Receptor |
| In Vivo | SKF-75670 hydrochloride (2.5-10 mg/kg，腹腔注射) 降低 MPTP 处理的狨猴的运动活性[2]。 SKF-75670 hydrochloride (0.3 和 1.0 mg/kg，肌肉注射) 拮抗可卡因对猴子的速率改变和辨别刺激作用[3]。 Animal Model: MPTP-treated marmosets[2] Dosage: 2.5-10 mg/kg Administration: i.p. Result: Reduced locomotor activity (marmosets were largely immobile and appeared sedated and had a flexed posture). |
| References |
| Boiling Point | 450.1ºC at 760 mmHg |
|---|---|
| Molecular Formula | C17H20BrNO2 |
| Molecular Weight | 350.25 |
| Flash Point | 241ºC |
| Exact Mass | 349.06800 |
| PSA | 43.70000 |
| LogP | 3.61360 |
