Resolution of the unique dopamine receptor agonist 2, 3, 4, 5-tetrahydro-7, 8-dihydroxy-l- phenyl-lH-3-benzazepine (1) was achieved by a stereospecific multistep conversion of the readily separated enantiomers of its O, O, N-trimethylated precursor 2. The absolute stereochemistry of the antipodes of &Me1 was determined by single-crystal X-ray diffractometric analysis, thus permitting assignment of the configuration of ...