- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Temozolomide-8-carboxylic acid
- Price: Check
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Temozolomide-8-carboxylic acid
- Price: ￥668.0/100mg ￥278.0/25mg
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: Temozolomide Acid
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Stocking Period: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: Temozolomide Acid
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 3-METHYL-4-OXO-3,4-DIHYDROIMIDAZO[5,1-D][1,2,3,5]TETRAZINE-8-CARBOXYLIC ACID
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
113942-30-6
113942-30-6 structure
- Name: Temozolomide-8-carboxylic acid
- Chemical Name: 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid
- CAS Number: 113942-30-6
- Molecular Formula: C6H5N5O3
- Molecular Weight: 195.136
- Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
- Create Date: 2018-12-25 16:31:27
- Modify Date: 2024-01-07 12:46:52
-
Temozolomide acid is a carboxylic acid derivative of Temozolomide. Temozolomide is a DNA alkylating agent, methylating the guanine and adenine bases of DNA, causing breaks in DNA double strand, cell cycle arrest, and eventually cell death. Temozolomide acid has an activity similar to the parent compound Temozolomide with the same anticancer activity[1].
| Name | 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid |
|---|---|
| Synonyms |
3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid
3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylic acid, 3,4-dihydro-3-methyl-4-oxo- Temozolomideacid Temozolomide-8-carboxylic acid |
| Description | Temozolomide acid is a carboxylic acid derivative of Temozolomide. Temozolomide is a DNA alkylating agent, methylating the guanine and adenine bases of DNA, causing breaks in DNA double strand, cell cycle arrest, and eventually cell death. Temozolomide acid has an activity similar to the parent compound Temozolomide with the same anticancer activity[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 2.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 487.7±37.0 °C at 760 mmHg |
| Melting Point | 177 ºC (decomp) |
| Molecular Formula | C6H5N5O3 |
| Molecular Weight | 195.136 |
| Flash Point | 248.7±26.5 °C |
| Exact Mass | 195.039246 |
| PSA | 102.38000 |
| LogP | -1.46 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.860 |
| Storage condition | 2-8°C |
| Water Solubility | Slightly soluble (4.3 g/L) (25 ºC) |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2933990090 |
|
~99%
113942-30-6 |
| Literature: Wang, Yongfeng; Lambert, Peter; Zhao, Linxiang; Wang, Danni European Journal of Medicinal Chemistry, 2002 , vol. 37, # 4 p. 323 - 332 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |