Temozolomide-8-carboxylic acid
Modify Date: 2024-01-07 12:46:52
Temozolomide-8-carboxylic acid structure
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Common Name | Temozolomide-8-carboxylic acid | ||
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| CAS Number | 113942-30-6 | Molecular Weight | 195.136 | |
| Density | 2.0±0.1 g/cm3 | Boiling Point | 487.7±37.0 °C at 760 mmHg | |
| Molecular Formula | C6H5N5O3 | Melting Point | 177 ºC (decomp) | |
| MSDS | N/A | Flash Point | 248.7±26.5 °C | |
Use of Temozolomide-8-carboxylic acidTemozolomide acid is a carboxylic acid derivative of Temozolomide. Temozolomide is a DNA alkylating agent, methylating the guanine and adenine bases of DNA, causing breaks in DNA double strand, cell cycle arrest, and eventually cell death. Temozolomide acid has an activity similar to the parent compound Temozolomide with the same anticancer activity[1]. |
| Name | 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Temozolomide acid is a carboxylic acid derivative of Temozolomide. Temozolomide is a DNA alkylating agent, methylating the guanine and adenine bases of DNA, causing breaks in DNA double strand, cell cycle arrest, and eventually cell death. Temozolomide acid has an activity similar to the parent compound Temozolomide with the same anticancer activity[1]. |
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| Related Catalog | |
| References |
| Density | 2.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 487.7±37.0 °C at 760 mmHg |
| Melting Point | 177 ºC (decomp) |
| Molecular Formula | C6H5N5O3 |
| Molecular Weight | 195.136 |
| Flash Point | 248.7±26.5 °C |
| Exact Mass | 195.039246 |
| PSA | 102.38000 |
| LogP | -1.46 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.860 |
| Storage condition | 2-8°C |
| Water Solubility | Slightly soluble (4.3 g/L) (25 ºC) |
| Hazard Codes | Xi |
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| HS Code | 2933990090 |
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~99%
Temozolomide-8-... CAS#:113942-30-6 |
| Literature: Wang, Yongfeng; Lambert, Peter; Zhao, Linxiang; Wang, Danni European Journal of Medicinal Chemistry, 2002 , vol. 37, # 4 p. 323 - 332 |
| Precursor 1 | |
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| DownStream 0 | |
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid |
| 3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid |
| Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylic acid, 3,4-dihydro-3-methyl-4-oxo- |
| Temozolomideacid |
| Temozolomide-8-carboxylic acid |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Temozolomide-8-carboxylic acid
- Price: ￥668.0/100mg ￥278.0/25mg
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Temozolomide Acid
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 3-METHYL-4-OXO-3,4-DIHYDROIMIDAZO[5,1-D][1,2,3,5]TETRAZINE-8-CARBOXYLIC ACID
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
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