Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (+/-)-2-PROPYLPIPERIDINEHYDROCHLORIDE*
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Purity: 98.0%
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15991-59-0

15991-59-0 structure

15991-59-0 structure

Name: 2-propylpiperidine hydrochloride
Chemical Name: (2S)-2-Propylpiperidine hydrochloride (1:1)
CAS Number: 15991-59-0
Molecular Formula: C₈H₁₈ClN
Molecular Weight: 163.69
Create Date: 2017-02-21 02:37:43
Modify Date: 2025-08-21 16:50:59
(±)-Coniine hydrochloride (2-Propylpiperidine hydrochloride) is a potent nAChR agonist with an EC50 value of 0.3 mM. (±)-Coniine hydrochloride shows acute toxicity with an LD50 value of 7.7 mg/kg[1].

Name	(2S)-2-Propylpiperidine hydrochloride (1:1)
Synonyms	(S)-2,2'-bis(diphenylphosphanyl)-5,5'-dichloro-6,6'-dimethoxy-1,1'-biphenyl (S)-3,7-Dimethyloct-6-enal (3S)-3,7-dimethyl-6-octenal (S)-(+)-coniine*HCl l-citronellal (-)-Citronellal (S)-2-propylpiperidine hydrochloride (S)-(-)-Citronellal (S)-(-)-5,5'-dichloro-6,6'-dimethoxy-2,2'-bis(diphenylphosphino)-1,1'-biphenyl (S)-Cl,OMe-BIPHEP (S)-coniine hydrochloride (3S)-(-)-Citronellal (S)-3,7-Dimethyl-6-octenal (+)-coniine hydrochloride (2S)-2-n-propylpiperidine hydrochloride (R)-Cl,MeO-BIPHEP (+)-(2S)-2-propylpiperidine hydrochloride (S)-Cl-MeO-BIPHEP

Description	(±)-Coniine hydrochloride (2-Propylpiperidine hydrochloride) is a potent nAChR agonist with an EC50 value of 0.3 mM. (±)-Coniine hydrochloride shows acute toxicity with an LD50 value of 7.7 mg/kg[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
Target	EC50: 0.3 mM (nAChR)[1]
In Vivo	(±)-Coniine hydrochloride (compound 1) (0.05 mg-0.2 mg; i.v.) 具有急性毒性，LD50 值为 7.7 mg/kg[1]。 Animal Model: 15-20 g, Swiss-Webster male mice[1] Dosage: 0.05 mg-0.2 mg Administration: I.v. Result: Clinical signs was almost immediate after injection, beginning with piloerection, tailflicking, and rapidly progressing to intention tremors, clonic convulsions, muscular weakness, lateral recumbency, and death; shows acute toxicity with an LD50 value of 7.7 mg/kg.
References	[1]. Lee ST, et al. Stereoselective potencies and relative toxicities of coniine enantiomers. Chem Res Toxicol. 2008 Oct;21(10):2061-4.

Boiling Point	166.2ºC at 760 mmHg
Melting Point	-210ºC(lit.)
Molecular Formula	C₈H₁₈ClN
Molecular Weight	163.69
Flash Point	48.4ºC
Exact Mass	163.11300
PSA	12.03000
LogP	3.05940
Vapour Pressure	1.8mmHg at 25°C

Hazard Codes	Xi: Irritant;
Risk Phrases	R36
Safety Phrases	S26
HS Code	2933399090

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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