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Product Name: Amiridine
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62732-44-9

62732-44-9 structure

Name: Ipidacrine
Chemical Name: 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine
CAS Number: 62732-44-9
Molecular Formula: C₁₂H₁₆N₂
Molecular Weight: 188.26900
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2018-12-23 09:39:42
Modify Date: 2025-08-25 19:07:25
2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine is a pharmaceutically active compound which is a nootropic agent that acts as cholinesterase inhibitor and is used in treatment of Alzheimer disease[1].

Name	2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine
Synonyms	Amiridine Ipidacrine 9-amino-2,3,5,6,7,8-hexahydro-1-cyclopenta<b>quinoline Amiridin

Description	2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine is a pharmaceutically active compound which is a nootropic agent that acts as cholinesterase inhibitor and is used in treatment of Alzheimer disease[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. A.Dubika, K. Veldre, et al. Phase Transitions of Ipidacrine Hydrochloride Polymorphs and Hydrates. The Open Conference Proceedings Journal, 2011, 2, 21-27.

Density	1.17 g/cm3
Boiling Point	367.969ºC at 760 mmHg
Molecular Formula	C₁₂H₁₆N₂
Molecular Weight	188.26900
Flash Point	203.991ºC
Exact Mass	188.13100
PSA	38.91000
LogP	2.61250
Index of Refraction	1.634

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GY5897400

CHEMICAL NAME :: 1H-Cyclopenta(b)quinolin-9-amine, 2,3,5,6,7,8-hexahydro-

CAS REGISTRY NUMBER :: 62732-44-9

BEILSTEIN REFERENCE NO. :: 0475930

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H16-N2

MOLECULAR WEIGHT :: 188.30

WISWESSER LINE NOTATION :: TC566 BNT&TJ HZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 39 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - miosis (pupillary constriction) Behavioral - tremor Gastrointestinal - hypermotility, diarrhea

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 11,184,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 52 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 23,709,1989

Hazard Codes	Xi

58996-10-4

~76%

62732-44-9

Literature: Upadysheva, A. V.; Grigor'eva, N. D.; Ryabokobylko, Yu. S.; Znamenskaya, A. P. Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , p. 95 - 99 Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 1 p. 107 - 111

108-94-1

2941-23-3

62732-44-9

Literature: Pharmaceutical Chemistry Journal, , vol. 26, # 9-10 p. 769 - 772 Khimiko-Farmatsevticheskii Zhurnal, , vol. 26, # 9-10 p. 83 - 85

Precursor 3
58996-10-4 108-94-1 2941-23-3
DownStream 0

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