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90043-86-0

90043-86-0 structure
90043-86-0 structure
  • Name: Ipidacrine hydrochloride
  • Chemical Name: 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine,hydrochloride
  • CAS Number: 90043-86-0
  • Molecular Formula: C12H17ClN2
  • Molecular Weight: 224.73000
  • Create Date: 2017-11-16 12:07:02
  • Modify Date: 2023-01-31 11:44:28
  • Ipidacrine hydrochloride is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels.

Name 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine,hydrochloride
Synonyms NIK 247
Ipidacrine hydrochloride
Amiridin
Boiling Point 368ºC at 760mmHg
Molecular Formula C12H17ClN2
Molecular Weight 224.73000
Flash Point 204ºC
Exact Mass 224.10800
PSA 38.91000
LogP 3.41450

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GY5925000
CHEMICAL NAME :
1H-Cyclopenta(b)quinoline, 2,3,5,6,7,8-hexahydro-9-amino-, monohydrochloride, hydrate
CAS REGISTRY NUMBER :
90043-86-0
LAST UPDATED :
198508
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C12-H16-N2.Cl-H.H2-O
MOLECULAR WEIGHT :
242.78

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
60 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BAXXDU British UK Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2125696
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
68 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BAXXDU British UK Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2125696
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
44 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BAXXDU British UK Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2125696
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
52 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BAXXDU British UK Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2125696
HS Code 2933990090
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%