Ipidacrine hydrochloride

Modify Date: 2025-08-26 16:05:19

Ipidacrine hydrochloride Structure
Ipidacrine hydrochloride structure
Common Name Ipidacrine hydrochloride
CAS Number 90043-86-0 Molecular Weight 224.73000
Density N/A Boiling Point 368ºC at 760mmHg
Molecular Formula C12H17ClN2 Melting Point N/A
MSDS N/A Flash Point 204ºC

 Use of Ipidacrine hydrochloride


Ipidacrine hydrochloride is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels.

 Names

Name 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine,hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 368ºC at 760mmHg
Molecular Formula C12H17ClN2
Molecular Weight 224.73000
Flash Point 204ºC
Exact Mass 224.10800
PSA 38.91000
LogP 3.41450
InChIKey FERZJAONQGPFCU-UHFFFAOYSA-N
SMILES Cl.Nc1c2c(nc3c1CCC3)CCCC2

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GY5925000
CHEMICAL NAME :
1H-Cyclopenta(b)quinoline, 2,3,5,6,7,8-hexahydro-9-amino-, monohydrochloride, hydrate
CAS REGISTRY NUMBER :
90043-86-0
LAST UPDATED :
198508
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C12-H16-N2.Cl-H.H2-O
MOLECULAR WEIGHT :
242.78

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
60 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BAXXDU British UK Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2125696
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
68 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BAXXDU British UK Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2125696
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
44 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BAXXDU British UK Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2125696
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
52 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BAXXDU British UK Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2125696

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

NIK 247
Ipidacrine hydrochloride
Amiridin
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