Uridine

Names

[ CAS No. ]:
58-96-8

[ Name ]:
Uridine

[Synonym ]:
1-β-δ-Ribofuranosyluracil
Uracil, 1-β-D-ribofuranosyl-
uracil riboside
EINECS 200-407-5
1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione
URD
1-b-D-Ribofuranosyluracil
Uracil-1-β-D-ribofuranoside
1-b-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione
1-(β-D-Ribofuranosyl)pyrimidin-2,4(1H,3H)-dion
NFDB2
1-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione
Uridine
D-URIDINE
MFCD00006526
T6NVMVJ A- BT5OTJ CQ DQ E1Q &&β-D-Ribo Form
2(1H)-Pyrimidinone, 4-hydroxy-1-β-D-ribofuranosyl-
2,4(1H,3H)-pyrimidinedione, 1-β-D-ribofuranosyl-
4-Hydroxy-1-(β-D-ribofuranosyl)-2(1H)-pyrimidinone
Uridin
Diquafosol Impurity 11

Biological Activity

[Description]:

Uridin is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond.

[Related Catalog]:

Natural Products >> Saccharides and Glycosides

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
567.9±60.0 °C at 760 mmHg

[ Melting Point ]:
163-167 °C(lit.)

[ Molecular Formula ]:
C₉H₁₂N₂O₆

[ Molecular Weight ]:
244.201

[ Flash Point ]:
297.2±32.9 °C

[ Exact Mass ]:
244.069534

[ PSA ]:
124.78000

[ LogP ]:
-1.55

[ Vapour Pressure ]:
0.0±3.5 mmHg at 25°C

[ Index of Refraction ]:
1.732

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YR1450000

CHEMICAL NAME :: Uracil, 1-beta-D-ribofuranosyl-

CAS REGISTRY NUMBER :: 58-96-8

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C9-H12-N2-O6

MOLECULAR WEIGHT :: 244.23

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4335 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay)

TYPE OF TEST :: Micronucleus test

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 100 mmol/L

REFERENCE :: PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 48,686,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1002 No. of Facilities: 35 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 115 (estimated) No. of Female Employees: 64 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
YR1450000

[ Packaging Group ]:
I; II; III

[ Hazard Class ]:
6.1

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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