H-Glu(OMe)-OMe.HCl

Names

[ Name ]:
H-Glu(OMe)-OMe.HCl

[Synonym ]:
dimethyl DL-glutamate hydrochloride
L-Glutamic acid, dimethyl ester, hydrochloride (1:1)
H-Glu(OMe)-OMeï¿½ï¿½HCl
H-Glu(OMe)-OMe·HCl
H-Glu(OMe)-OMe.HCl
H-Glu(OMe)-OMe,HCl
(S)-Dimethyl 2-aminopentanedioate hydrochloride
L-Glutamicaciddimethylesterhydrochloride
MFCD00038879
DiMethyl L-GlutaMate Hydrochloride
L-Glutamic acid dimethyl ester hydrochloride
Dimethyl L-glutamate hydrochloride (1:1)
EINECS 245-461-0

Biological Activity

[Description]:

Glutamic acid dimethyl ester hydrochloride is a glutamic acid derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.129g/cm3

[ Boiling Point ]:
224.3ºC at 760 mmHg

[ Melting Point ]:
89-90°C

[ Molecular Formula ]:
C₇H₁₄ClNO₄

[ Molecular Weight ]:
211.643

[ Flash Point ]:
76.7ºC

[ Exact Mass ]:
211.061142

[ PSA ]:
78.62000

[ LogP ]:
0.94220

[ Vapour Pressure ]:
0.0919mmHg at 25°C

[ Index of Refraction ]:
26 ° (C=5, H2O)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Preparation

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Effects of the methyl esters of pyruvate, succinate and glutamate on the secretory response to meglitinide analogues in rat pancreatic islets.

Pharmacol. Res. 33(3) , 191-4, (1996)

The insulinotropic action of the meglitinide analogues KAD-1229, A-4166 and repaglinide was examined in rat pancreatic islets deprived of exogenous nutrient or incubated in the presence of nutrient se...

Potentiation and prolongation of the insulinotropic action of glucagon-like peptide 1 by methyl pyruvate or dimethyl ester of L-glutamic acid in a type 2 diabetes animal model.

Endocrine 16(2) , 113-6, (2001)

Methyl pyruvate and the dimethyl ester of L-glutamic acid were administered intravenously, as a primed constant infusion (1.0-2.0 micromol followed by 0.5-1.0 micromol/min, both expressed per gram of ...

Spectrum of toxicities of amino acid methyl esters for myeloid cells is determined by distinct metabolic pathways.

Blood 79(4) , 964-71, (1992)

L-leucine methyl ester (Leu-OMe), Leu-Leu-OMe, Phe-OMe, and Glu-(OMe)2 are toxic to mononuclear phagocytes (M phi) and neutrophils. In the present studies, the mechanism of this toxicity was examined....