Chlorotrimethylsilane
Names
[ CAS No. ]:
75-77-4
[ Name ]:
Chlorotrimethylsilane
[Synonym ]:
Chlorotrimethylsilane
MFCD00000502
EINECS 200-900-5
chloro(trimethyl)silane
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
58.7±9.0 °C at 760 mmHg
[ Melting Point ]:
−40 °C(lit.)
[ Molecular Formula ]:
C3H9ClSi
[ Molecular Weight ]:
108.642
[ Flash Point ]:
-27.8±0.0 °C
[ Exact Mass ]:
108.016205
[ LogP ]:
2.17
[ Vapour density ]:
3.7 (vs air)
[ Vapour Pressure ]:
219.8±0.1 mmHg at 25°C
[ Index of Refraction ]:
1.388
[ Stability ]:
Stable. Highly flammable - note low flash point. Reacts violently with water. Incompatible with water, moisture, strong oxidizing agents, strong acids, strong bases, aldehydes, alcohols, amines, esters, ketones.
[ Water Solubility ]:
REACTS
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VV2710000
- CHEMICAL NAME :
- Silane, chlorotrimethyl-
- CAS REGISTRY NUMBER :
- 75-77-4
- BEILSTEIN REFERENCE NO. :
- 1209232
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C3-H9-Cl-Si
- MOLECULAR WEIGHT :
- 108.66
- WISWESSER LINE NOTATION :
- G-SI-1&1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5660 uL/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - other changes
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Immunological Including Allergic - decreased immune response
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1780 uL/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1000 mg/kg/I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 1 mg/plate
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 8(Suppl 7),1,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83272 No. of Facilities: 59 (estimated) No. of Industries: 3 No. of Occupations: 4 No. of Employees: 200 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83272 No. of Facilities: 8 (estimated) No. of Industries: 2 No. of Occupations: 15 No. of Employees: 1876 (estimated) No. of Female Employees: 20 (estimated)
Safety Information
[ Symbol ]:
GHS02, GHS05, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H301 + H331-H312-H314
[ Supplemental HS ]:
Corrosive to the respiratory tract., Reacts violently with water.
[ Precautionary Statements ]:
P210-P261-P280-P301 + P310-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US)
[ Hazard Codes ]:
C:Corrosive
[ Risk Phrases ]:
R11;R14;R21;R34
[ Safety Phrases ]:
S26-S36/37/39-S45-S16-S36/37
[ RIDADR ]:
UN 2924 3/PG 2
[ WGK Germany ]:
2
[ RTECS ]:
VV2710000
[ Packaging Group ]:
II
[ Hazard Class ]:
3
[ HS Code ]:
29310095
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 29310095
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