N-(4-aminobenzoyl)-L-glutamic acid

Names

[ Name ]:
N-(4-aminobenzoyl)-L-glutamic acid

[Synonym ]:
4-AMINOBENZOYLGLUTAMIC ACID
N-(4-Aminobenzoyl)-L-glutamic acid
4-aminobenzoyl-L-glutamic acid
L-Glutamic acid, N-(4-aminobenzoyl)-
P-AMINO BENZAMIDE GLUTAMIC ACID
N-(4-aminobenzoyl)-L-Glutamic acid,Folic Ac
N-(p-Aminobenzoyl)glutamic acid
p-aminobenzoyl-l-glutamic acid
Folic acid impurity A
(S)-2-(4-Aminobenzamido)pentanedioic acid
(p-aminobenzoyl)-L-glutamic acid
EINECS 224-261-7
N-(p-Aminobenzoyl)-L-glutamic acid
4-Aminobenzoyl-L-glutaminsaeure
H-4-ABZ-GLU-OH
L-N-(p-Aminobenzoyl)glutamic acid
4-AMINOBENZOIC GLUTAMIC ACID
Glutamic acid, N- (p-aminobenzoyl)-, L-
L-Glutamic acid, N- (4-aminobenzoyl)-
N-p-aminobenzoyl-L-glutamic acid
MFCD00042821
Methotrexate Impurity 11

Biological Activity

[Description]:

(4-Aminobenzoyl)-L-glutamic acid is a glutamic acid derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
607.1±55.0 °C at 760 mmHg

[ Melting Point ]:
~175 °C (dec.)

[ Molecular Formula ]:
C₁₂H₁₄N₂O₅

[ Molecular Weight ]:
266.250

[ Flash Point ]:
321.0±31.5 °C

[ Exact Mass ]:
266.090271

[ PSA ]:
129.72000

[ LogP ]:
-0.99

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.618

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922421000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Simultaneous quantification of 21 water soluble vitamin circulating forms in human plasma by liquid chromatography-mass spectrometry.

J. Chromatogr. A. 1422 , 89-98, (2015)

This manuscript reports a validated analytical approach for the quantification of 21 water soluble vitamins and their main circulating forms in human plasma. Isotope dilution-based sample preparation ...

Photodegradation of folic acid in aqueous solution.

J. Pharm. Biomed. Anal. 19 , 269-275, (1999)

A study of the photodegradation of folic acid by ultraviolet radiation in aqueous solution has been made. Folic acid is photolysed by an apparent first-order kinetics and the log k-pH profile shows a ...

Kinetic model of folate metabolism in nonpregnant women consuming [2H2]folic acid: isotopic labeling of urinary folate and the catabolite para-acetamidobenzoylglutamate indicates slow, intake-dependent, turnover of folate pools.

J. Nutr. 128(11) , 1896-906, (1998)

In a 10-wk study of folate metabolism in nonpregnant women (21-27 y, n -6 per group), subjects were fed a diet containing approximately 68 nmol/d (30 microg/d) folate from food. The remainder of the i...