ATR-IN-14
Names
[ CAS No. ]:
2765785-88-2
[ Name ]:
ATR-IN-14
Biological Activity
[Description]:
ATR-IN-14 (compound 1) is a potent ATR kinase inhibitor. ATR-IN-14 inhibits ATR signaling pathways downstream CHKI protein phosphorylation, with inhibition of 98.03% at 25 nM. ATR-IN-14 shows good anticancer activity in LoVo cells, with an IC50 of 64 nM[1].
[Related Catalog]:
[Target]
ATR
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C20H20FN7O
[ Molecular Weight ]:
393.42