ATR-IN-15
Names
[ CAS No. ]:
2756665-52-6
[ Name ]:
ATR-IN-15
Biological Activity
[Description]:
ATR-IN-15 (compound 1) is an orally active and potent ATR kinase inhibitor, with an IC50 of 8 nM. ATR-IN-15 also inhibits human colon tumor cells LoVo, DNA-PK and PI3K, with IC50 values of 47, 663 and 5131 nM, respectively[1].
[Related Catalog]:
[Target]
ATR:8 nM (IC50)
PI3K:5131 nM (IC50)
ATM:> 10000 nM (IC50)
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C19H22N8O
[ Molecular Weight ]:
378.43