ATR-IN-8

Names

[ CAS No. ]:
2672511-20-3

[ Name ]:
ATR-IN-8

Biological Activity

[Description]:

ATR-IN-8 is a potent inhibitor of ATR. ATR is a key enzyme in the homologous recombination repair pathway and belongs to the PIKK family. ATR-IN-8 has the potential for the research of cancer diseases (extracted from patent WO2021143821A1, compound 3)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> ATM/ATR
Signaling Pathways >> PI3K/Akt/mTOR >> ATM/ATR

[References]

[1]. Li Xin, et al. Thickened heteroaryl derivatives, their preparation methods and their application in medicine. Patent WO2021143821A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H22N6O2S

[ Molecular Weight ]:
410.49

Related Compounds