2'-deoxyuridine
Names
[ CAS No. ]:
951-78-0
[ Name ]:
2'-deoxyuridine
[Synonym ]:
Uracildeoxyr
deoxyuridine
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-hydroxy-2(1H)-pyrimidinone
T6NVMVJ A- ET5OTJ B1Q CQ &&Ribo-β-D Form
2'-deoxy-uridin
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-
1-(2-Deoxy-b-D-erythro-pentofuranosyl)uracil
[131I]-Deoxyuridine
2'-Deoxyuridine
Desoxyuridine
Uridine, 2'-deoxy-
MFCD00006527
2'-dU
EINECS 213-455-7
1-(2-Deoxy-D-erythro-pentofuranosyl)uracil
Deoxyribose uracil
1-(2-deoxy-β-D-ribofuranosyl)-2,4(1H,3H)-Pyrimidinedione
Deoxy-uridin
2′-Deoxyuridine
2(1H)-Pyrimidinone, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-4-hydroxy-
[3H]-Deoxyuridine
1-(2-deoxy-β-D-erythro-pentofuranosyl)uracil
1-(2-deoxy-β-δ-erythro-pentofuranosyl)-2,4(1H,3H)-Pyrimidinedione
1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
durd
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-ribofuranosyl)-
1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione
1-(2-deoxy-β-δ-ribofuranosyl)-2,4(1H,3H)-Pyrimidinedione
DEOXYURIDINE-2'
1-(2-deoxy-β-D-erythro-pentofuranosyl)-2,4(1H,3H)-Pyrimidinedione
1-(2-Deoxy-β-D-erythro-pentofuranosyl)pyrimidin-2,4(1H,3H)-dion
2'-DEOXYTHYMIDINE-5'-DIPHOSPHATE TRISODIUM SALT
1-(2-Deoxy-δ-erythro-pentofuranosyl)uracil
Biological Activity
[Description]:
[Related Catalog]:
[Target]
Human Endogenous Metabolite
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Melting Point ]:
167-169 °C(lit.)
[ Molecular Formula ]:
C9H12N2O5
[ Molecular Weight ]:
228.202
[ Exact Mass ]:
228.074615
[ PSA ]:
104.55000
[ LogP ]:
-1.70
[ Index of Refraction ]:
1.603
[ Storage condition ]:
0-6°C
[ Water Solubility ]:
300 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YU7490000
- CHEMICAL NAME :
- Uridine, 2'-deoxy-
- CAS REGISTRY NUMBER :
- 951-78-0
- BEILSTEIN REFERENCE NO. :
- 0024433
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C9-H12-N2-O5
- MOLECULAR WEIGHT :
- 228.23
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 1 mmol/L
- REFERENCE :
- BICMBE Biochimie. (SPPIF, B.P.22, F-41353 Vineuil, France) V.53- 1971- Volume(issue)/page/year: 64,809,1982
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S22-S24/25-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
YU7490000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Chromatogr. A. 1356 , 197-210, (2014)
Improved nitrogen utilization in cattle is important in order to secure a sustainable cattle production. As purines and pyrimidines (PP) constitute an appreciable part of rumen nitrogen, an improved u...
Phase I study of oral gemcitabine prodrug (LY2334737) in Japanese patients with advanced solid tumors.Cancer Chemother. Pharmacol. 71(6) , 1645-55, (2013)
LY2334737 is an oral gemcitabine prodrug. This Phase I study assessed the safety and tolerability of LY2334737 in Japanese patients with solid tumors and evaluated pharmacokinetics (PK), pharmacodynam...
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.J. Med. Chem. 51 , 6740-51, (2008)
The work provides a new model for the prediction of the MAO-A and -B inhibitor activity by the use of combined complex networks and QSAR methodologies. On the basis of the obtained model, we prepared ...