3-Hydroxypicolinic acid

Names

[ CAS No. ]:
874-24-8

[ Name ]:
3-Hydroxypicolinic acid

[Synonym ]:
3-Hydroxypyridine-2-carboxylic acid
2-Carboxy-3-hydroxypyridine
RARECHEM AL BO 0972
3-Hydroxypicolinic acid
hydroxypicolinic acid
3-Hydroxy-2-carboxypyridine
3-hydroxy-picolinic acid
EINECS 212-859-0
3-Hydroxy-2-pyridine carboxylic acid
2-Pyridinecarboxylic acid, 3-hydroxy-
3-hydroxy-pyridine-2-carboxylic acid
3-Hydroxy-2-pyridinecarboxylic acid
MFCD00006294
3-Hydroxy-2-Pyridinecarboxylic

Biological Activity

[Description]:

3-Hydroxypicolinic acid is a picolinic acid derivative, and belongs to the pyridine family.

[Related Catalog]:

Research Areas >> Others

Natural Products >> Alkaloid

[Target]

Human Endogenous Metabolite

[References]

[1]. Tang K, et al. Picolinic acid as a matrix for laser mass spectrometry of nucleic acids and proteins. Rapid Commun Mass Spectrom. 1994 Sep;8(9):673-7.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
451.1±30.0 °C at 760 mmHg

[ Melting Point ]:
213-218 °C(lit.)

[ Molecular Formula ]:
C₆H₅NO₃

[ Molecular Weight ]:
139.109

[ Flash Point ]:
226.6±24.6 °C

[ Exact Mass ]:
139.026947

[ PSA ]:
70.42000

[ LogP ]:
0.72

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.626

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/22;R36/37/38

[ Safety Phrases ]:
S26-S28-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis of PS/PO-chimeric oligonucleotides using mixed oxathiaphospholane and phosphoramidite chemistry.

Org. Biomol. Chem. 13(1) , 269-76, (2014)

Chimeric oligonucleotides containing phosphodiester and phosphorothioate linkages have been obtained using the solid phase synthesis. The oligonucleotide parts possessing natural internucleotide phosp...

Electrochemiluminescent DNA sensor based on controlled Zn-mediated grafting of diazonium precursors.

Anal. Bioanal. Chem 407 , 5579-86, (2015)

Controlled Zn-mediated grafting of a thin layer of a diazonium salt was used to functionalise a carbon electrode with ruthenium(II)-tris-bipyridine (Ru)-labelled DNA for use as a capture probe in an e...

Identifying chelators for metalloprotein inhibitors using a fragment-based approach.

J. Med. Chem. 54 , 591-602, (2011)

Fragment-based lead design (FBLD) has been used to identify new metal-binding groups for metalloenzyme inhibitors. When screened at 1 mM, a chelator fragment library (CFL-1.1) of 96 compounds produced...