UDPGA

Names

[ Name ]:
UDPGA

[Synonym ]:
TrisodiumUDP glucuronic acid
Trisodium (2S,3S,4S,5R,6R)-6-({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-3,4-dihydroxytetrahydro-2-furanyl]methoxy}phosphinato)oxy]phosphinato}oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate
URIDINE-5'-DIPHOSPHO-GLUCURONIC ACID
Trisodium (2S,3S,4S,5R)-6-({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-3,4-dihydroxytetrahydro-2-furanyl]methoxy}phosphinato)oxy]phosphinato}oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate
uridine-5'-diphosphoglucuronic acid trisodium salt
MFCD00037687
UDP-diphosphoglucuronic acid trisodium salt
uridine diphosphate glucuronic acid trisodium salt

Biological Activity

[Description]:

UDP-glucuronic acid trisodium is a critical precursor for essential glycoconjugates across biological kingdoms, ranging from mammalian glycosaminoglycans and plant cell wall polysaccharides to bacterial capsule glycoglycerolipids.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Li LX, et al. UDP-Glucuronic Acid Transport Is Required for Virulence of Cryptococcus neoformans. MBio. 2018 Jan 30;9(1). pii: e02319-17.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₉N₂Na₃O₁₈P₂

[ Molecular Weight ]:
646.231

[ Exact Mass ]:
645.980103

[ PSA ]:
342.17000

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

Precursor & DownStream

Precursor

DownStream

Articles

In vitro and in vivo biotransformation of WMS-1410, a potent GluN2B selective NMDA receptor antagonist.

J. Pharm. Biomed. Anal. 94 , 36-44, (2014)

Structural modification of the GluN2B selective NMDA receptor antagonist ifenprodil led to the 3-benzazepine WMS-1410 with similar GluN2B affinity but higher receptor selectivity. Herein the in vitro ...

Metabolic drug-drug interaction potential of macrolactin A and 7-O-succinyl macrolactin A assessed by evaluating cytochrome P450 inhibition and induction and UDP-glucuronosyltransferase inhibition in vitro.

Antimicrob. Agents Chemother. 58(9) , 5036-46, (2014)

Macrolactin A (MA) and 7-O-succinyl macrolactin A (SMA), polyene macrolides containing a 24-membered lactone ring, show antibiotic effects superior to those of teicoplanin against vancomycin-resistant...

Simultaneous determination of intracellular UDP-sugars in hyaluronic acid-producing Streptococcus zooepidemicus.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 997 , 194-9, (2015)

Two chromatographic methods for the quantitative analysis of uridine diphosphate (UDP) sugars involved in hyaluronan pathway of Streptococcus zooepidemicus (SEZ) were developed and compared. The sampl...