α-D-Glucopyranuronic acid

Names

[ Name ]:
α-D-Glucopyranuronic acid

[Synonym ]:
α-D-glucuronic acid
D-Glucuronic acid
EINECS 229-486-4
D-Glucopyranuronic acid
MFCD00077778
(2S,3S,4S,5R)-2,3,4,5-Tetrahydroxy-6-oxohexanoic acid

Biological Activity

[Description]:

D-Glucuronic acid is an important intermediate isolated from many gums. D-Glucuronic acid and its derivative glucuronolactone are as a liver antidote in the prophylaxis of human health. D-Glucuronic acid has an anti-inflammatory effect for the skin[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

[References]

[1]. Teng F, et al. Production of d-glucuronic acid from myo-inositol using Escherichia coli whole-cell biocatalyst overexpressing a novel myo-inositol oxygenase from Thermothelomyces thermophile. Enzyme Microb Technol. 2019 Aug;127:70-74.

Chemical & Physical Properties

[ Density]:
2.0±0.1 g/cm3

[ Boiling Point ]:
495.2±45.0 °C at 760 mmHg

[ Melting Point ]:
159-161ºC(lit.)

[ Molecular Formula ]:
C₆H₁₀O₇

[ Molecular Weight ]:
194.139

[ Flash Point ]:
211.1±22.2 °C

[ Exact Mass ]:
194.042648

[ PSA ]:
135.29000

[ LogP ]:
-2.88

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.685

[ Storage condition ]:
Refrigerator (+4°C)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
37/39-26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
LZ8836600

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Extraction optimization, characterization and antioxidant activity in vitro of polysaccharides from mulberry (Morus alba L.) leaves.

Carbohydr. Polym. 128 , 52-62, (2015)

Extraction optimization, characterization and antioxidant activity in vitro of polysaccharides from mulberry leaves (MLP) were investigated in the present study. The optimal extraction conditions with...

Modulation of biomechanical properties of hyaluronic acid hydrogels by crosslinking agents.

J. Biomed. Mater. Res. A 103 , 3072-80, (2015)

Modulation of both mechanical properties and biocompatibilities of hyaluronic acid (HA) hydrogels is very importance for their applications in biomaterials. Pure HA solution was converted into a hydro...

GlxA is a new structural member of the radical copper oxidase family and is required for glycan deposition at hyphal tips and morphogenesis of Streptomyces lividans.

Biochem. J. 469 , 433-44, (2015)

Streptomyces lividans displays a distinct dependence on copper to fully initiate morphological development. Evidence has accumulated to implicate the participation of an extracytoplasmic cuproenzyme i...