4-Nitrophenyl β-D-glucopyranosiduronic acid

Names

[ Name ]:
4-Nitrophenyl β-D-glucopyranosiduronic acid

[Synonym ]:
EINECS 233-753-0
4-NITROPHENYL-β-D-GLUCURONIDE
MFCD00036210
4-Nitrophenyl β-D-glucopyranosiduronic acid
4-Nitrophenyl-beta-D-glucuronide
β-D-Glucopyranosiduronic acid, 4-nitrophenyl
4-Nitrophenyl β-D-Glucuronide [Substrate
4-Nitrophenyl b-D-glucosiduronic acid

Biological Activity

[Description]:

4-Nitrophenyl β-D-glucuronide (pNPG_1) is aderivative of 4-nitrophenol 4-Nitrophenyl β-D-glucuronide is a chromogenic compound and is the chromogenic substrate for β-glucuronidase[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. A Mariscal, et al. Interference by carbohydrate substrates, flavonoids, and monosaccharide derivatives on bacterial beta-D-glucuronidase assays. Arch Environ Contam Toxicol. 1998 Nov;35(4):588-93.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
644.4±55.0 °C at 760 mmHg

[ Melting Point ]:
93°C

[ Molecular Formula ]:
C₁₂H₁₃NO₉

[ Molecular Weight ]:
315.233

[ Flash Point ]:
343.5±31.5 °C

[ Exact Mass ]:
315.059021

[ PSA ]:
162.27000

[ LogP ]:
-0.75

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.675

[ Storage condition ]:
−20°C

[ Water Solubility ]:
H2O: 0.1 g/mL, clear, faintly yellow

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

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Indian J. Exp. Biol. 52(10) , 965-71, (2014)

In vitro study revealed that pancreatic lipase inhibitory activity of C. asiatica extract was significantly higher than rutin but lower than orlistat, an anti-obesity drug. alpha-Amylase inhibitory ac...

Engineering the genome of Thermus thermophilus using a counterselectable marker.

J. Bacteriol. 197(6) , 1135-44, (2015)

Thermus thermophilus is an extremely thermophilic bacterium that is widely used as a model thermophile, in large part due to its amenability to genetic manipulation. Here we describe a system for the ...

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

J. Med. Chem. 51 , 3275-87, (2008)

The chemical space of registered oral drugs was explored for inhibitors of the human multidrug-resistance associated protein 2 (MRP2; ABCC2), using a data set of 191 structurally diverse drugs and dru...

Related Compounds

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