6-Shogaol
Names
[ CAS No. ]:
555-66-8
[ Name ]:
6-Shogaol
[Synonym ]:
(E)-1-(4-Hydroxy-3-methoxy-phenyl)-dec-4-en-3-one
(4E)-1-(4-Hydroxy-3-methoxyphenyl)dec-4-en-3-one
6-Shogaol
Trans-6-Shogaol
MFCD01736094
4-Decen-3-one, 1-(4-hydroxy-3-methoxyphenyl)
Shogaol
4-Decen-3-one, 1-(4-hydroxy-3-methoxyphenyl)-, (4E)-
(4E)-1-(4-Hydroxy-3-methoxyphenyl)-4-decen-3-one
[6]-Shogaol
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
[In Vivo]
[Cell Assay]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
427.5±35.0 °C at 760 mmHg
[ Molecular Formula ]:
C17H24O3
[ Molecular Weight ]:
276.371
[ Flash Point ]:
150.3±19.4 °C
[ Exact Mass ]:
276.172546
[ PSA ]:
46.53000
[ LogP ]:
3.85
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.522
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HE2097000
- CHEMICAL NAME :
- 4-Decen-3-one, 1-(4-hydroxy-3-methoxyphenyl)-
- CAS REGISTRY NUMBER :
- 555-66-8
- LAST UPDATED :
- 199410
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C17-H24-O3
- MOLECULAR WEIGHT :
- 276.41
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 687 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 109 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50900 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 700 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 122,87,1983
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
22
[ RIDADR ]:
NONH for all modes of transport
Articles
Crit. Rev. Food Sci. Nutr 51(6) , 499-523, (2011)
The rhizomes of Zingiber officinale Roscoe (Zingiberaceae), commonly known as ginger, is one of the most widely used spice and condiment. It is also an integral part of many traditional medicines and ...
In vitro antioxidant and anti-inflammatory activities of 1-dehydro-[6]-gingerdione, 6-shogaol, 6-dehydroshogaol and hexahydrocurcumin.Food Chem. 135(2) , 332-7, (2012)
Hexahydrocurcumin, 1-dehydro-[6]-gingerdione, 6-dehydroshogaol and 6-shogaol were evaluated for their antioxidant and anti-inflammatory activities in the present study. The relative antioxidant potenc...
6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor γ (PPARγ).Cancer Lett. 336(1) , 127-39, (2013)
6-Shogaol has been shown to possess many antitumor properties including inhibition of cancer cell growth, inhibition of cancer metastasis, induction of apoptosis in cancer cells and induction of cance...