(+)-Camphor

Names

[ CAS No. ]:
464-49-3

[ Name ]:
(+)-Camphor

[Synonym ]:
(1R,4R)-1,7,7-trimethylnorbornan-2-one
(+)-bornan-2-one
Alcanfor
Bicyclo(2.2.1)heptan-2-one, 1,7,7-trimethyl-
Camphor, (1R,4R)-(+)-
UNII:5TJD82A1ET
(+)-2-Bornanone
D-CAMPHOR
2-Bornanone,2-Camphanone,D-Camphor
EINECS 207-355-2
D-(+)-Camphor
DL-2-Bornanone
(+)-Camphor
(1R,4R)-camphor
1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one
DL-Camphor
Bicyclo(2.2.1)heptan-2-one, 1,7,7-trimethyl-, (1R,4R)-
(1R,4R)-1,7,7-Trimethylbicyclo(2.2.1)heptan-2-one
2-Keto-1,7,7-trimethylnolcamphane
Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-
Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1R,4R)-
(±)-Camphor
(1R)-(+)-Camphor
2-Camphonone
Camphor
2-Bornanone,2-Camphanone
D(+)-Camphor
2-Bornanone 2-Camphanone
(+)-Camphor,(1R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one
MFCD00064149
(1R,4R)-(+)-CAMPHOR
(R)-(+)-camphor
(1R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one
EINECS 207-355-2

Biological Activity

[Description]:

(+)-Camphor is an ingredient in cooking, and as an embalming fluid for medicinal purposes,

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial

Research Areas >> Others

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
207.4±0.0 °C at 760 mmHg

[ Melting Point ]:
176-180ºC

[ Molecular Formula ]:
C₁₀H₁₆O

[ Molecular Weight ]:
152.233

[ Flash Point ]:
64 ºC

[ Exact Mass ]:
152.120117

[ PSA ]:
17.07000

[ LogP ]:
2.13

[ Vapour density ]:
5.24 (vs air)

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.485

[ Stability ]:
Stable. Incompatible with strong reducing agents, strong oxidizing agents, chlorinated solvents. Protect from direct sunlight.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EX1260000

CHEMICAL NAME :: Camphor, (1R,4R)-(+)-

CAS REGISTRY NUMBER :: 464-49-3

LAST UPDATED :: 199701

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C10-H16-O

MOLECULAR WEIGHT :: 152.26

WISWESSER LINE NOTATION :: L55 A CVTJ A1 A1 B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,665,1978 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,665,1978

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,665,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1310 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,665,1978

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,665,1978

TYPE OF TEST :: LD90 - Lethal Dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 525 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,665,1978

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,665,1978 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 4 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - other effects

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB92-170034

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H228-H302-H315-H319-H335

[ Precautionary Statements ]:
P210-P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
F;Xi

[ Risk Phrases ]:
R11;R36/37/38

[ Safety Phrases ]:
S16-S26-S37/39

[ RIDADR ]:
UN 2717 4.1/PG 3

[ WGK Germany ]:
1

[ RTECS ]:
EX1260000

[ Packaging Group ]:
III

[ Hazard Class ]:
4.1

[ HS Code ]:
2914299000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914299000

[ Summary ]:
2914299000. other cyclanic, cyclenic or cyclotherpenic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Carvacrol and rosemary essential oil manifest cytotoxic, DNA-protective and pro-apoptotic effect having no effect on DNA repair.

Neoplasma 61(6) , 690-9, (2014)

For several thousand years natural products were successfully used to treat a variety of diseases and to maintain health in humans, but until now it is not fully known what causes these medicinal effe...

In vitro antifungal activity and probable fungicidal mechanism of aqueous extract of Barleria grandiflora.

Appl. Biochem. Biotechnol. 175(8) , 3571-84, (2015)

Barleria grandiflora Dalz. (Acanthaceae) is being used in India to treat different types of disorders including skin infections. Therefore, there are good possibilities to find antifungal compounds in...

Development and application of a non-targeted extraction method for the analysis of migrating compounds from plastic baby bottles by GC-MS.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 31(12) , 2090-102, (2014)

In 2011, the European Union prohibited the production of polycarbonate (PC) baby bottles due to the toxic effects of the PC monomer bisphenol-A. Therefore, baby bottles made of alternative materials, ...