Glycitin

Names

[ Name ]:
Glycitin

[Synonym ]:
BIDD:ER0468
4',7-Dihydroxy-6-methoxyisoflavone-7-D-glucoside
3-(4-Hydroxyphenyl)-6-methoxy-4-oxo-4H-chromen-7-yl b-D-glucopyranoside
MFCD00800711
Glycitein 7-O-|A-glucoside
Glycitein-7-|A-O-glucoside
Glycitein 7-O-β-D-glucoside
3-(4-Hydroxyphenyl)-6-methoxy-4-oxo-4H-chromen-7-yl β-D-glucopyranoside
4H-1-Benzopyran-4-one
4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-6-methoxy-
Glycitin
Glycitein 7-O-glucoside

Biological Activity

[Description]:

Glycitin is a natural isoflavone isolated from legumes; promotes the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Others

Natural Products >> Flavonoids

[References]

[1]. Uesugi T, et al. Comparative study on reduction of bone loss and lipid metabolism abnormality in ovariectomized rats by soy isoflavones, daidzin, genistin, and glycitin. Biol Pharm Bull. 2001 Apr;24(4):368-72.

[2]. Li XH, et al. Effect of daidzin, genistin, and glycitin on osteogenic and adipogenic differentiation of bone marrow stromal cells and adipocytic transdifferentiation of osteoblasts. Acta Pharmacol Sin. 2005 Sep;26(9):1081-6.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
751.1±60.0 °C at 760 mmHg

[ Melting Point ]:
210ºC

[ Molecular Formula ]:
C₂₂H₂₂O₁₀

[ Molecular Weight ]:
446.404

[ Flash Point ]:
264.1±26.4 °C

[ Exact Mass ]:
446.121307

[ PSA ]:
159.05000

[ LogP ]:
0.16

[ Vapour Pressure ]:
0.0±2.6 mmHg at 25°C

[ Index of Refraction ]:
1.675

[ Storage condition ]:
Store at -20

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Effects of naturally occurring isoflavones on prostaglandin E2 production.

Planta Med. 68 , 97-100, (2002)

Previously, we reported that the isoflavones tectorigenin and tectoridin, a glycosylated tectorigenin, isolated from the rhizomes of Belamcanda chinensis have an activity to inhibit prostaglandin (PG)...

Isoflavone glycosides from the flowers of Pueraria thunbergiana. Park HJ

Phytochemistry 51 , 147-151, (1999)