Loganetin

Names

[ Name ]:
Loganetin

[Synonym ]:
Methyl (1R,4aS,6S,7R,7aS)-1,6-dihydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate
loganin aglycone
Arsanilsaeure-N-oxalylsaeure
4-Oxalamino-phenylarsonsaeure
Cyclopenta[c]pyran-4-carboxylic acid, 1,4a,5,6,7,7a-hexahydro-1,6-dihydroxy-7-methyl-, methyl ester, (1R,4aS,6S,7R,7aS)-
Loganetin
p-Arsonooxanilic acid
loganigenin

Biological Activity

[Description]:

Loganetin is a non-toxic natural product that may be applied in the antibacterial drug development for treating multidrug-resistant Gram negative infections.

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial

Research Areas >> Infection

Natural Products >> Others

[In Vitro]

Although Loganetin does not possess antibacterial activity of its own, but in combination, it appreciably reduces the minimum inhibitory concentration (MIC) of nalidixic acid (NA) against nalidixic acid resistant (NAREC) and nalidixic acid sensitive (NASEC) strains of Escherichia coli. Loganetin, a very common, inexpensive, and non-toxic natural product may finds its application in the antibacterial drug development for treating multidrug-resistant Gram negative infections[1].

[References]

[1]. Anupam Maurya, et al. Preparative Isolation of Bioenhancer Loganetin from sf Alstonia scholaris by Fast Centrifugal Partition Chromatography. Separation Science and Technology Volume 49, 2014-Issue 5.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
375.7±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₆O₅

[ Molecular Weight ]:
228.242

[ Flash Point ]:
145.5±21.4 °C

[ Exact Mass ]:
228.099777

[ PSA ]:
75.99000

[ LogP ]:
-0.61

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.542

[ Storage condition ]:
2-8℃

Loganetin

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds