29748-10-5

29748-10-5 structure

Name: Loganetin
Chemical Name: Methyl (1R,4aS,6S,7R,7aS)-1,6-dihydroxy-7-methyl-1,4a,5,6,7,7a-he xahydrocyclopenta[c]pyran-4-carboxylate
CAS Number: 29748-10-5
Molecular Formula: C₁₁H₁₆O₅
Molecular Weight: 228.242
Catalog: Natural product Iridoid derivative
Create Date: 2017-09-27 18:08:42
Modify Date: 2024-01-14 16:56:39
Loganetin is a non-toxic natural product that may be applied in the antibacterial drug development for treating multidrug-resistant Gram negative infections.

Name	Methyl (1R,4aS,6S,7R,7aS)-1,6-dihydroxy-7-methyl-1,4a,5,6,7,7a-he xahydrocyclopenta[c]pyran-4-carboxylate
Synonyms	Methyl (1R,4aS,6S,7R,7aS)-1,6-dihydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate loganin aglycone Arsanilsaeure-N-oxalylsaeure 4-Oxalamino-phenylarsonsaeure Cyclopenta[c]pyran-4-carboxylic acid, 1,4a,5,6,7,7a-hexahydro-1,6-dihydroxy-7-methyl-, methyl ester, (1R,4aS,6S,7R,7aS)- Loganetin p-Arsonooxanilic acid loganigenin

Description	Loganetin is a non-toxic natural product that may be applied in the antibacterial drug development for treating multidrug-resistant Gram negative infections.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection Natural Products >> Others
In Vitro	Although Loganetin does not possess antibacterial activity of its own, but in combination, it appreciably reduces the minimum inhibitory concentration (MIC) of nalidixic acid (NA) against nalidixic acid resistant (NAREC) and nalidixic acid sensitive (NASEC) strains of Escherichia coli. Loganetin, a very common, inexpensive, and non-toxic natural product may finds its application in the antibacterial drug development for treating multidrug-resistant Gram negative infections[1].
References	[1]. Anupam Maurya, et al. Preparative Isolation of Bioenhancer Loganetin from sf Alstonia scholaris by Fast Centrifugal Partition Chromatography. Separation Science and Technology Volume 49, 2014-Issue 5.

Precursor 0
DownStream 2
91668-36-9 99891-77-7