ATR-IN-16

Names

[ CAS No. ]:
2756589-62-3

[ Name ]:
ATR-IN-16

Biological Activity

[Description]:

ATR-IN-16 (compound 46) is a potent ATR kinase inhibitor. ATR-IN-16 shows good anticancer activity in LoVo cells, with an IC50 of 410 nM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> ATM/ATR
Signaling Pathways >> PI3K/Akt/mTOR >> ATM/ATR

[Target]

ATR


[References]

[1]. Bo Shan, et al. Atr inhibitors and uses thereof. WO2022002245A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H25N7O

[ Molecular Weight ]:
367.45

Related Compounds