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oleoylglycine

Names

[ CAS No. ]:
2601-90-3

[ Name ]:
oleoylglycine

[Synonym ]:
Glycine, N-[(9Z)-1-oxo-9-octadecen-1-yl]-
N-(1-Oxo-9-octadecenyl)-(Z)-glycine
N-[(9Z)-9-Octadecenoyl]glycine
oleoylglycine
N-Oleoylglycine
N-[(9Z)-Octadec-9-enoyl]glycine

Biological Activity

[Description]:

N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte.

[Related Catalog]:

Signaling Pathways >> PI3K/Akt/mTOR >> Akt
Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor
Research Areas >> Metabolic Disease
Natural Products >> Others

[Target]

Human Endogenous Metabolite

CB1 Receptor

Akt


[In Vitro]

N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte. N-Oleoyl glycine (1, 5, 10, 20, 50 μM) dose- and time-dependently stimulates 3T3-L1 adipogenesis after treatment for 1-10 days via activation of CB1R. N-Oleoyl glycine also elevates Akt signaling pathway during the differentiation of 3T3-L1 adipocytes[1].

[References]

[1]. Wang S, et al. N-Oleoyl glycine, a lipoamino acid, stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte. Biochem Biophys Res Commun. 2015 Oct 23;466(3):438-43.


[Related Small Molecules]

3-Methyladenine | SB203580 | MK-2206 2HCl | Hydrocortisone | Acetylcysteine(N-acetylcysteine) | Retinoic acid | Melatonine | SC79 | Dinoprostone | Nicotinamide | Capivasertib (AZD5363) | Adenosine triphosphate | Honokiol | 4-Acetamidophenol | Prostaglandin E1

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
525.6±43.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H37NO3

[ Molecular Weight ]:
339.513

[ Flash Point ]:
271.7±28.2 °C

[ Exact Mass ]:
339.277344

[ PSA ]:
66.40000

[ LogP ]:
6.57

[ Vapour Pressure ]:
0.0±3.0 mmHg at 25°C

[ Index of Refraction ]:
1.478

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds