Ac-Arg-OH

Names

[ CAS No. ]:
155-84-0

[ Name ]:
Ac-Arg-OH

[Synonym ]:
n2-acetyl-l-arginin
Ac-Arg-OH.2H2O
N(alpha)-acetyl-L-arginine
N-ACETYL-L-ARGININE
EINECS 205-846-6
AC-ARG-OH
Ac-L-Arg-OH
MFCD00019733
N2-acetyl-L-arginine
N-α-ACETYL-L-ARGININE
N5-Amidino-N2-acetyl-L-ornithine
N-acetyl-L-Arg
AC-ARGININE

Biological Activity

[Description]:

Ac-Arg-OH is one of the guanidino compounds found elevated in the serum of an hemodialyzed renal insufficient (uremic) pediatric population.

[Related Catalog]:

Natural Products >> Others

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. De Deyn PP, et al. Serum guanidino compound levels in uremic pediatric patients treated with hemodialysis or continuous cycle peritoneal dialysis. Correlations between nerve conduction velocities and altered guanidino compound concentrations. Nephron. 1995;69(4):411-7.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.39g/cm3

[ Molecular Formula ]:
C₈H₁₆N₄O₃

[ Molecular Weight ]:
216.23800

[ Exact Mass ]:
216.12200

[ PSA ]:
128.30000

[ LogP ]:
0.42080

[ Index of Refraction ]:
1.58

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2925290090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

3-hydroxykynurenine-mediated modification of human lens proteins: structure determination of a major modification using a monoclonal antibody.

J. Biol. Chem. 280 , 22154-22164, (2005)

Tryptophan can be oxidized in the eye lens by both enzymatic and non-enzymatic mechanisms. Oxidation products, such as kynurenines, react with proteins to form yellow-brown pigments and cause covalent...

Early glycation products produce pentosidine cross-links on native proteins. novel mechanism of pentosidine formation and propagation of glycation.

J. Biol. Chem. 276(6) , 3895-903, (2001)

Bovine lens alpha-crystallin was immobilized on EAH-Sepharose gel and glycated using d-ribose. Incubation with 500 and 100 mm d-ribose for 2 and 15 days produced short-term glycated (STGP gel) and lon...

Influence of 72% injury in one kidney on several organs involved in guanidino compound metabolism: a time course study.

Pflugers Arch. 442(4) , 558-69, (2001)

Arginine (Arg) produced from citrulline originates mostly from kidneys. Arg is involved in guanidino compound biosynthesis, which requires interorgan co-operation. In renal insufficiency, citrulline a...