<Suppliers Price>

Azido-PEG2-C2-acid

Names

[ CAS No. ]:
1312309-63-9

[ Name ]:
Azido-PEG2-C2-acid

[Synonym ]:
Propanoic acid, 3-[2-(2-azidoethoxy)ethoxy]-
3-[2-(2-Azidoethoxy)ethoxy]propanoic acid
MFCD20926378
Azido-PEG2-acid
Azido-PEG3-acid

Biological Activity

[Description]:

Azido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

[ Molecular Formula ]:
C7H13N3O4

[ Molecular Weight ]:
203.196

[ Exact Mass ]:
203.090607

[ LogP ]:
-0.35

Related Compounds