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Amino-PEG2-C2-acid

Names

[ CAS No. ]:
791028-27-8

[ Name ]:
Amino-PEG2-C2-acid

[Synonym ]:
Propanoic acid, 3-[2-(2-aminoethoxy)ethoxy]-
3-[2-(2-Aminoethoxy)ethoxy]propanoic acid
H2N-PEG2-COOH

Biological Activity

[Description]:

Amino-PEG2-C2-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Antibody drug conjugate, intermediate, preparation method, pharmaceutical composition and uses thereof. WO2016197946A1.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
331.5±27.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H15NO4

[ Molecular Weight ]:
177.198

[ Flash Point ]:
154.3±23.7 °C

[ Exact Mass ]:
177.100113

[ LogP ]:
-1.21

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.467

[ Storage condition ]:
2-8°C


Related Compounds