Vanilpyruvic acid

Names

[ Name ]:
Vanilpyruvic acid

[Synonym ]:
vanilpyruvate
3-Methoxy-4-hydroxyphenylbrenztraubensaeure
4-Hydroxy-3-methoxyphenylpyruvic acid
4-Oxy-3-methoxy-phenylbrenztraubensaeure
Hmppa cpd
4-Hydroxy-3-methoxy-phenylbrenztraubensaeure
Vanilpyruvic acid

Biological Activity

[Description]:

Vanilpyruvic acid is a catecholamine metabolite and precursor to vanillactic acid.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

Signaling Pathways >> Membrane Transporter/Ion Channel >> Monoamine Transporter

Signaling Pathways >> GPCR/G Protein >> Opioid Receptor

Signaling Pathways >> Neuronal Signaling >> Opioid Receptor

Research Areas >> Neurological Disease

[In Vitro]

The catecholamines, dopamine, norepinephrine, and epinephrine, constitute a class of chemical neurotransmitters and hormones that occupy key positions in the regulation of physiological processes and the development of neurological, psychiatric, endocrine, and cardiovascular diseases[1]. Catecholamines, namely dopamine (3,4-dihydrophenylethylamine), norepinephrine (noradrenaline) and epinephrine (adrenaline), act as neurotransmitters or hormones at central and peripheral levels. In addition to being the most abundant of the monoamine neurotransmitters, dopamine is also found in non-neuronal tissues such as the gastrointestinal tract and the kidney, where it participates in the regulation of sodium balance[2].

[References]

[1]. Eisenhofer G, et al. Catecholamine metabolism: a contemporary view with implications for physiology and medicine. Pharmacol Rev. 2004 Sep;56(3):331-49.

[2]. Bicker J, et al. Liquid chromatographic methods for the quantification of catecholamines and their metabolites in several biological samples--a review. Anal Chim Acta. 2013 Mar 20;768:12-34.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.374g/cm3

[ Boiling Point ]:
402ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₁₀O₅

[ Molecular Weight ]:
210.18300

[ Flash Point ]:
162.1ºC

[ Exact Mass ]:
210.05300

[ PSA ]:
83.83000

[ LogP ]:
0.59700

[ Vapour Pressure ]:
3.49E-07mmHg at 25°C

[ Index of Refraction ]:
1.575

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%