Danshensu lactic acid

Names

[ Name ]:
Danshensu lactic acid

[Synonym ]:
salvianic acid A
salvianic acid
a-Hydroxyhydrocaffeic acid
Danshensu lactic acid
alpha,3,4-Trihydroxy-benzenepropanoic acid

Biological Activity

[Description]:

(Rac)-Salvianic acid A ((Rac)-Danshensu), a phenolic acids, is an efficient radical scavenger and antioxidant[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

(Rac)-Salvianic acid A ((Rac)-Danshensu) exhibits higher scavenging activities against free hydroxyl radicals (HO), superoxide anion radicals (O2), 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radicals and 2-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radicals than vitamin C[1].

[In Vivo]

(Rac)-Salvianic acid A ((Rac)-Danshensu; i.v.; 30 mg/kg) has a T1/2 of 16.6 min in rabbits[2].

[References]

[1]. Guang-Rong Zhao, et al. Characterization of the radical scavenging and antioxidant activities of danshensu and salvianolic acid B. Food Chem Toxicol. 2008 Jan;46(1):73-81.

[2]. Limin Zhou, et al. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005 Dec;45(12):1345-59.

Chemical & Physical Properties

[ Density]:
1.54g/cm3

[ Boiling Point ]:
480.3ºC at 760mmHg

[ Molecular Formula ]:
C₉H₁₀O₅

[ Molecular Weight ]:
198.17300

[ Flash Point ]:
258.4ºC

[ Exact Mass ]:
198.05300

[ PSA ]:
97.99000

[ LogP ]:
0.08580

[ Water Solubility ]:
Freely soluble (285 g/L) (25 ºC)

Safety Information

[ HS Code ]:
2918290000

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918290000

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%