P2X7 receptor antagonist-2
Modify Date: 2024-01-29 17:32:49
P2X7 receptor antagonist-2 structure
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Common Name | P2X7 receptor antagonist-2 | ||
|---|---|---|---|---|
| CAS Number | 851269-75-5 | Molecular Weight | 377.264 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 640.1±55.0 °C at 760 mmHg | |
| Molecular Formula | C19H18Cl2N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 340.9±31.5 °C | |
Use of P2X7 receptor antagonist-2P2X7 receptor antagonist-2 is a potent P2X7 receptor antagonist with a pIC50 value of 6.5-7.5. P2X7 receptor antagonist-2 has efficacy of combating neuroinflammation[1]. |
| Name | 1-Benzyl-N-(2,4-dichlorobenzyl)-5-oxo-3-pyrrolidinecarboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | P2X7 receptor antagonist-2 is a potent P2X7 receptor antagonist with a pIC50 value of 6.5-7.5. P2X7 receptor antagonist-2 has efficacy of combating neuroinflammation[1]. |
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| Related Catalog | |
| Target |
pIC50：6.5-7.5 (P2X7 receptor)[1] |
| References |
[1]. Steadman JGA, et, al. 5-oxo-3-pyrrolidinecarboxamide derivatives as p2x7 modulators. WO2009077559A2 |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 640.1±55.0 °C at 760 mmHg |
| Molecular Formula | C19H18Cl2N2O2 |
| Molecular Weight | 377.264 |
| Flash Point | 340.9±31.5 °C |
| Exact Mass | 376.074524 |
| LogP | 2.87 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.622 |
| 1-Benzyl-N-(2,4-dichlorobenzyl)-5-oxo-3-pyrrolidinecarboxamide |
| 3-Pyrrolidinecarboxamide, N-[(2,4-dichlorophenyl)methyl]-5-oxo-1-(phenylmethyl)- |